L4LM’s Miami Music Week Diary

first_imgIt’s the craziest week in dance music every single year. At the end of March, music fans and industry workers travel from all across the globe to South Beach, Miami, Florida, for a week of mixers, parties, festivals, and clubs. Every where you look, there’s something going on. If there is a space big enough for some turntables and some speakers, chances are, there will be a party going on. Even in the smallest hotel lobbies, someone will be spinning shitty techno music until 6am.It’s hard work to catch everything you want to see – but I tried my best, and documented the whole thing. Here’s a day by day diary of what went down this past week in Miami.TuesdayThe opening day is still quiet in Miami. The music industry have all arrived, meetings are beind held, but the throngs of kandi wearing tourists have not yet arrived for Ultra Music Festival over the weekend. There’s stuff to do – several small pool parties here and there, but this was a good day to relax and take in the calm before the storm.At night, however, things are completely different, as the Above and Beyond was set to perform at Mansion. As one of the hottest acts in dance music right now, this was one of the few events of the early week to completely sell out – and you could tell. Mansion was packed from wall to wall with eager dance fans looking to take in a helping of Above and Beyond’s heartfeld dance music. While once considered a trance act, I feel like Above and Beyond has carved out their own genre at this point. This set was no different, blending progressive electronic beats with soulful lyrics and never losing the party.WednesdayOne of the new entries to this year’s party scene was also one of the most highly anticipated – Good Times Miami debuted with an entirely new concept, bringing partiers a day full of back to back sets and new collaborations. Curated by Skrillex’s OWSLA records, Weds’ line up included an incredible hip hop based set from Boys Noize and Brodinski, which featured an appearance from Baltimore rapper Spank Rock, the legendary Benny Bennassi going b2b with Congorock, and an incredible display of turntablism with A-Trak spinning next to DJ Craze. Those turntable masters, next to each other, switching off, was one of the crazier thing’s I’d see all week. If you were lucky, you also caught Skrillex messing around with some audio equipment backstage, performing for a crowd of maybe 10 or 15 people.Wednesday night sent me to Story for Laidback Luke’s ‘Super You And Me’ party, which is supposed to have a super hero theme, but saw most party goers all decked out in their fancies. Laidback Luke put out a predictable awesome set, captivating the crowd with an incredible set. Support for the night included DJ Snake, who’se song ‘Turn Down For What’ was arguable to most overplayed song of this year’s Miami Music Week (in a loving way), and The Chainsmokers, who had a camera crew running around taking selfies for a remix video they’re working on.ThursdayI dont know if this was a conscious effort, but Thursday was the most packed day in terms of things going on everywhere. But before anything really started, Armin Van Buuren was hosting a press conference, announcing his brand new Phillips headphones. These things are incredible, folding up tight for travel, completely customizable side pieces, and a bunch of other features that only a true DJ would appreciate. Those of us who stuck around were treated to a brief set from Armin himself, going through some of his bigger hits in an intimate setting.After Armin, it was off to the Dirtybird BBQ, one of the most highly anticipated parties of the year. Claude VonStroke brought the whole crew to the Cafeina Wynwood Lounge, a fantastic outdoor space, and threw down a party that started early and ended late. Unlike last year’s event, this one went wayyy into the early morning – you could have spent the entire day at the BBQ. This year’s special guest was hip hop legend Just Blaze, who went through hip hop history with a slew of his greatest productions. It was a welcome change, but I think everyone was ready to get back to the deep cuts with Claude VonStroke hit the decks, followed by Justin Martin, with the two superstars destroying the dance floor.Another highly anticipated event took place at night not too far away – Mau5trap vs Pryda saw two dance music heavyweights share the same booth for the first time – completely unrehearsed and unplanned. Both labels brought their future stars for support, including Eekoo, Fehrplay, and Jeremy Olander, but the main attraction was the label heads themselves. Deadmau5 manned his laptop and controllers, Prydz took the CDJs, and the two put on an incredible show for the packed floor of mau5heads that danced the night away.FridayThe Red Bull Guest House kicked off Friday with a pool party curated by Skrillex’s OWSLA label. The invite only party saw sets from Kill The Noise, What So Not, Milo and Otis, and of course, Skrillex, in a pretty tiny pool area. Oh, and there was an ice cream man that forced you to dance to earn free ice cream bars, tons of weird performance artists, and a huge floating Red Bull logo in the pool that you couldn’t help but dance on. Skrillex’s set was a huge highlight, as he erred towards newer influences of deep and progressive house, and away from the womps and wobbles that made him famous.After a short break, it was back to the Red Bull Guest House for their late night ‘Breakfast Club’, which turns the inside of the Gale Hotel into, well, a breakfast club. From 2:30-7, DJs transform two rooms into night clubs, and the lobby becomes a breakfast buffet, complete with modern fortune tellers, open bar, and a full food spread. Downstairs saw PMR Records’ showcase acts like Julio Bashmore, Cyril Hahn, and T. Williams, while upstairs saw the LuckyMe Collective show off such up and coming stars as Cashmere Cat and Obey City. Due to the way the club was laid out, few people knew Cashmere Cat was spinning upstairs, and his set was pretty much empty, but hey, I enjoyed standing right next to the booth while I got a private Cashmere Cat show. (Seriously, there were times when I was the only other person in the room). Obey City took the decks after, and they must have shut down the downstairs as the crowd ended up all bouncing to the upstairs midway through the set. The bigger crowd added to the energy and the DJ ended up performing a long, long set.SaturdayThe Red Bull Guest House was in full effect again, this time with a day curated by Mad Decent Records. Sets from Zeds Dead, Djemba Djemba, Grandtheft, among others filled up the day, along with a special surprise b2b set from Diplo and DJ Snake. Hip hop appearances from Riff Raff, Wakka Flocka Flame, and Trinidad James rounded out the day’s festivities. In Downtown Miami, the Anjunadeep pool party was in full swing, along with special guest Dusky who showed up for a surprise set. Saturday night saw Dusky perform a three hour set downstairs at Trade, while upstiars Maceo Plez went back to back with Danny Daze for an incredible set of deeper house music. Earlier in the night, Diddy debuted a new track with Guy Gerber before Gerber took the decks at Red Bull Guest House. SundayThe last day of Miami Music Week also saw one of the more highly anticipated sets of the weekend. While the previous days saw the likes of Skrillex and Diplo manned the Red Bull Guest House in previous days, it was 73 year old Giorgio Moroder who threw down the biggest party of the weekend. The legendary producer took to the booth late in the afternoon in the backyard area, moved from pool side to accomodate a bigger crowd. He then spun for around an hour and half, seemingly not wanting to stop. Every time the music, would cut, he’d come back for one more, eventually reprising songs like ‘Hot Stuff’ and ‘I Feel Love’ once more for encores. Throughout his set, Moroder weaved in and out of his classic productions, including the themes from ‘Flashdance’, ‘Neverending Story’, ‘Top Gun’, and ‘Midnight Express’. Throughout the entire weekend, I dont think there was a greater reaction to any set I saw than Moroders, and I think that’s a fitting end to the week – with the man whose responsible for influencing many of the DJs who headlined the big shows throughout the weekend.last_img read more

New source of heart stem cells discovered

first_imgHarvard Stem Cell Institute(HSCI) researchers at Children’s Hospital Boston are continuing to document the heart’s earliest origins. Now, they have pinpointed a new, previously unrecognized group of stem cells that give rise to cardiomyocytes, or heart muscle cells. These stem cells, located in the surface of the heart, or epicardium, advance the hope of being able to regenerate injured heart tissue.This finding, published online by the journal Nature, comes on the heels of parallel cardiac stem cell discoveries in 2006, by HSCI scientists at both Children’s and Massachusetts General Hospital (MGH).Then, the Children’s team found that a specific stem cell or progenitor, marked by expression of a gene called Nkx2-5, forms many components of the heart: heart muscle cells, vascular smooth muscle cells, and the endothelial cells lining blood vessels in the heart’s left-sided chambers. The team at MGH found a related progenitor, marked by expression of the Isl1 gene, that produces these same cell-types in the right-sided heart chambers. Now, researchers at Children’s have shown that heart muscle cells can also be derived from a third type of cardiac progenitor, located within the epicardium and identifiable through its expression of a gene called Wt1.  “There’s a lot of interest in finding places to obtain new cardiomyocytes, because in heart failure, you lose cardiomyocytes, so the only way to reverse heart failure is to make more of these cells,” said William Pu, a pediatric cardiologist at Children’s Hospital and HSCI Principal Faculty member who was the study’s senior investigator. Although epicardial cells are known to give rise to smooth muscle and endothelial cells during coronary vessel formation, nobody previously thought that epicardial cells might turn into cardiomyocytes. “I couldn’t believe it at first, myself,” said Bin Zhou, a research fellow in Pu’s laboratory and the study’s first author. The results were independently corroborated by researchers from the University of California, San Diego (UCSD). Using a different genetic marker, Tbx18, the UCSD team also showed that cardiomyocytes can be derived from the epicardium: their study will be published in the same issue of Nature.Pu and Zhou showed that a specific population of cells in the epicardium, marked by Wt1 expression, not only differentiated into cardiomyocytes, but also smooth muscle cells, endothelial cells, and fibroblasts (found in connective tissue).“If you’re going to regenerate a tissue, you need to regenerate the whole tissue, not just the cardiomyocytes,” said Pu. “This progenitor population contains all the potential to regenerate multiple tissue types within the heart.” In recent years, the scientific literature has described many progenitors for cardiomyocytes, Pu added, but the markers used frequently did not play a direct role in heart development. For example, Sca-1 and c-Kit are markers that most stem cells express throughout the body, with no cardiac or developmental specificity.“I think our best chance of getting a cell to do what we want is to modify what it was designed to do,” Pu elaborated. “Some of these other progenitors were isolated in the adult heart, but we don’t know what they do in the normal heart, and what they’re related to in the embryo. However, we clearly know what progenitors expressing Wt1, Nkx2-5, and Isl1 do in the fetus: They can make fibroblasts, blood vessels, and cardiomyocytes. Therefore we think we have a good shot, in the adult heart, of recapitulating these events.”Pu considers his and Zhou’s discovery to be a fortunate accident. They were trying, instead, to study a different gene, GATA4, by deleting it in the epicardium. “The tool we created for that experiment irreversibly marks the cells involved, so you can see where their descendants are headed in normal development,” Pu explained. “Unexpectedly, we saw that these epicardial cells were becoming cardiomyocytes — it was a lucky observation.” Using an enzyme called Cre recombinase, Pu and Zhou labeled epicardial cells in live mouse embryos with red fluorescent protein (RFP). Each time the Wt1 gene in these cells was activated, RFP lit up. Since the marker is inherited by descendants of the Wt1-expressing cell, the researchers could identify these descendants by looking for RFP. “If the marker shows up in a cardiomyocyte, then I know that cardiomyocyte came from the Cre-expressing progenitor,” said Pu.At the moment, scientists are still trying to figure out whether and how the Wt1-expressing progenitors relate to the progenitors reported in 2006. “What we think is that very early on, our particular progenitor expresses Nkx2-5 and Isl1, but quickly loses expression of both and starts expressing Wt1,” said Pu. “Think of a lineage hierarchy with Nkx2-5 and Isl1 at the top, and Wt1 as a branch. These two lineages separate pretty early, before the heart is present in the embryo. However, the Wt1-expressing progenitor may retain some of the developmental capabilities of the progenitors expressing Nkx2-5 and Isl1.” Pu and Zhou now want to know whether the epicardium in an adult mouse could be induced to make cardiomyocytes. “If so, obviously this would be much more translatable to human studies,” Pu said. Other ongoing questions are whether this newly discovered progenitor is truly multipotent (able to turn into all other cell types), how multipotency is controlled, and whether this can be used therapeutically to benefit adults with heart failure.The fact that the Wt1-expressing progenitors can also differentiate into fibroblasts in the developing heart suggests that they can contribute to scar formation in the adult heart after injury, Pu added. “But if we can turn the progenitors away from making scars, and instead turn them towards making cardiomyocytes, that would be pretty exciting.” Put another way, Pu and Zhou would love to learn what controls a progenitor’s choice — to become a fibroblast, a smooth muscle cell, or a cardiomyocyte — and develop ways of “biasing progenitors to make the choice or choices we want,” says Pu. “We still don’t know how we can manipulate these progenitors, and there’s no way to predict which ones will be useful. But I think having more choices is good, because then hopefully one of them will work.”last_img read more

Stage & Screen Star David Cassidy Dead at Age 67

first_imgDavid Cassidy(Photo: Getty Images) Broadway alum and The Partridge Family star David Cassidy died on November 21 at age 67 as a result of liver failure, according to The New York Times. Known for playing Keith Partridge on The Partridge Family, Cassidy rose to stardom as a teen and went on to be a major showman of both the stage and screen.Cassidy’s Broadway credits include Blood Brothers, Joseph and the Amazing Technicolor Dreamcoat and The Fig Leaves Are Falling. He garnered an Emmy Award nomination in 1978 for an appearance on Police Story. His numerous screen credits include Ironside, Bonanza, Malcolm in the Middle and many more. Cassidy also had a successful music career; his debut solo album Cherish peaked at nine on the Billboard Hot 100 in 1971.Born on April 12, 1950, in New York City to the actors Jack Cassidy and Evelyn Ward, Cassidy is survived by his son, Beau, his daughter, Katie, his stepmother Shirley Jones, and three half-brothers: Shaun, Patrick and Ryan. View Commentslast_img read more

What’s Holding You Back?

first_imgWhether you’re working on improving yourself personally or professionally, it’s essential to have the ability to be introspective and analytical, in order to identify what you need to work on.That’s also true when you’re coaching others.In that, self-improvement has a lot in common with troubleshooting systems and equipment at work: Diagnose, Analyze, Repair, Test, Prevent.I’m not going to spend this entire column beating on that analogy. I’ll give it a rest and move on after pointing out that with either troubleshooting or coaching, you spend your time identifying and fixing what’s not working, as opposed to what’s working fine.It’s a normal tendency to want to focus on the things that we’re already good at doing. I’ve often said that no one’s ever won a medal at the Olympics in their worst sport. But a long-term improvement in performance comes from recognizing weak points and working on them until either they’re no longer weaknesses, or, ideally, they become strengths. Systematically approaching weaknesses like that, one after another, and improving them is what coaching and self-improvement are all about.If you’re a sales manager, even if your sales team is good, and delivering good results, it’s still important to look for opportunities to help them grow. None of us is perfect; even your best salespeople always have something they can improve on. The same is true for salespeople: Finding ways to improve what you do and how you do it is what will take your production to the next level.When it comes to identifying opportunities for improvement, there’s endless grist for this mill, so let’s recognize one of the most common: lack of confidence — more specifically, lacking the belief that what you are presenting to clients is something that they will want. The importance of belief in yourself and your products and services is everything. Assuming that you’ve qualified the client correctly after asking questions and listening to their answers, your proposals should be on target.As harsh as it sounds, as a salesperson if you don’t have a deeply rooted belief that your products or services are worthwhile, you’re shooting yourself in the foot. I think that all of us can think back to instances where we didn’t make a sale, or we made a smaller sale than we could have because we lacked the confidence to go for broke. It was a lesson that I learned way back in the earliest days of my first job in retail. And it’s something that I’m still confronted with from time to time.This past fall, the company I worked for launched a new product that, to be completely honest, most of us found baffling. I don’t want to get too much into it here and swerve hard into self-promotion. Suffice to say that it’s a product that if you’re charitable, you would call revolutionary, and if you were cynical, you’d call crazy. Long story short: We, the people whose job is to promote and sell it, found ourselves dealing with Fear, Uncertainty and Doubt over our own product. It took some effort, and a bit of a trip outside the comfort zone to get our heads around it, and find both the belief in its necessity and the value proposition we could present to our resellers.I bring that up to underline that no matter how long you’ve been at this, you’ll find you’ll need to revisit the same ground more than once as work to improve yourself and your results. Prepare for it, and embrace it.last_img read more

CABA Pro Bono Project receives $150,000

first_imgCABA Pro Bono Project receives $150,000 OLIVIA RODRIGUEZ, from the left, Sen. Anitere Flores, R-Miami; Rep. Jose Felix Diaz, R-Miami; Lesley Mendoza, Maria Garcia, Annie Hernandez, and Giselle G. Madrigal.CABA Pro Bono Project receives $150,000 The Cuban American Bar Association (CABA) recently held an event at Marlins Park benefiting the CABA Pro Bono Project. Members of the Miami-Dade Legislative Delegation, including Sen. Anitere Flores, R-Miami, and Rep. Jose Felix Diaz, R-Miami, presented CABA Pro Bono Project with a check for $150,000. Approximately 40 child clients were able to attend the event and experience their first Major League Baseball game. “I am extremely grateful to the Miami Dade Delegation for their continuous support,” said Lesley Mendoza, executive director at the CABA Pro Bono Project. “Funding provided by the State of Florida allows us to continue to passionately serve our community by providing free legal services to those that are most in need.” The mission of the CABA Pro Bono Project is to assist the indigent community in Miami-Dade County by serving as a nexus and providing a referral source between needy clients and pro bono attorneys who can provide direct legal services to them. Practice areas include unaccompanied minors, foreclosure, immigration, and divorce clinics. For more information about becoming involved in the project, contact Mendoza at [email protected] July 15, 2016 Regular Newslast_img read more

Gophers’ Cinderella run ends with Big Ten Championship

first_imgGophers’ Cinderella run ends with Big Ten ChampionshipMinnesota won in a penalty shootout 5-4 after a 0-0 draw.Ellen SchmidtApril Bockin dribbles down the field during the game against DePaul on Thursday, Aug. 30 at Elizabeth Lyle Robbie Stadium. Erik NelsonNovember 5, 2018Jump to CommentsShare on FacebookShare on TwitterShare via EmailPrintThe Gophers were underdogs at every turn. The No. 7 seed against the No. 2, against the No. 6, finally for all the glory against the No. 1.Some didn’t expect the Gophers to beat the Nittany Lions in the Big Ten championship. Minnesota proved the critics wrong.Minnesota (11-8-2) defeated No. 15 Penn State (15-5-1) 5-4 on penalty kicks after a 0-0 draw on Sunday at Grand Park in Westfield, Indiana. The Gophers, who were seeded seventh in the Big Ten tournament, clinched their second Big Ten championship in three seasons.Head coach Stefanie Golan said this year’s Big Ten title feels different than the 2016 run.“It was special to be able to take that No. 1 seed all the way through and win the whole thing,” Golan said. “This one, going in as the seventh seed, there’s not as much pressure … because nobody outside your own locker room expects you to be able to do it at the end of the day.”Forward Makenzie Langdok put Minnesota ahead 5-4 in the seventh round of the shootout. Goalkeeper Maddie Nielsen clinched the Big Ten championship for the Gophers when she denied Nittany Lions midfielder Frankie Tagliaferri moments after Langdok scored.Langdok said she sprinted to Nielsen after the stop.“That was an unbelievable save,” Langdok said. “She did a great job in the shootout. She guessed right every time. All we have to do is put our PKs in and leave it up to her because we know she’ll get the rest of it done.”Nielsen jumped in celebration after making the shootout-winning save. Her teammates ran out to her as it became official: Minnesota had won the Big Ten championship. Nielsen was named the Defensive Most Outstanding Player of the tournament. She did not concede a goal during the tournament.“I was trying to stand up tall so they wouldn’t try to shove me over to the ground and do a dogpile,” Nielsen said. “Seeing all my teammates make their PKs and ending [the shootout] with a save made it all the better.”After neither team could score in regulation and overtime, the Big Ten championship match went to penalties for the first time in history. Nielsen’s save clinched Minnesota’s third Big Ten title since the program began in 1993.Nielsen said she credits Minnesota’s defense for her recent success.“They’ve been so strong in front of me,” she said. “Our communication has been going well. Knowing that I have full confidence in them and [that] they have full confidence in me has helped us succeed.”The Gophers automatically qualify for the NCAA tournament as Big Ten champions. Minnesota will learn its first-round opponent when the NCAA Tournament Selection Show airs online at NCAA.com on Monday at 3:30 p.m.Golan said she is proud of Minnesota for not letting doubters define its tournament.“I am super proud of this team for not caring what anybody else thinks,” Golan said. “To be able to lift that trophy at the end was great for them.”last_img read more

Udall, Smith, Introduce Bill To Expand Health Care Resources For Urban Indian Health Organizations Amid Pandemic

first_imgU.S. SENATE News:WASHINGTON, D.C. — U.S. Sen Tom Udall (D-N.M.) joined Senators Tina Smith (D-Minn.), James Lankford (R-Okla.) and Martha McSally (R-Ariz.) to introduce bipartisan legislation to boost health resources for urban Indian health organizations (UIOs) as they respond to the COVID-19 pandemic. The senators’ legislation comes as UIOs across the country face major funding and staff shortfalls, in addition to shortages in medical equipment and Personal Protective Equipment (PPE). These hardships have forced three UIOs across the country to close their doors while pushing many other facilities to the brink.The Indian Health System is made up of the Indian Health Service, Tribal health programs, and UIOs. UIOs provide culturally competent care for the over 70 percent of American Indians and Alaska Natives who live in urban centers. Currently, providers at UIOs are not offered the same malpractice liability protection as all other Indian Health Care Providers. The Coverage for Urban Indian Health Providers Act would amend the Indian Health Care Improvement Act to create parity within the Indian Health System (I/T/U system).The legislation would expand Federal Torts Claim Act coverage (FTCA) to UIOs, which are currently required to divert already-limited resources away from patient care to cover liability costs. “Urban Indian health programs funded by the IHS are facing revenue shortfalls while ramping up services to combat the COVID-19 pandemic. And, as a result, many of these critical health care programs are struggling to keep the lights on and their doors open. They shouldn’t be the only branch of the IHS that has to divert resources away from health care services to cover exorbitant liability costs,” Udall said. “The federal government’s trust and treaty responsibilities to Native Americans do not stop at reservation boundaries. Nearly 70 percent of American Indians and Alaska Natives live in urban areas and Congress must ensure they have access to quality health care — especially during this public health crisis. This legislation is a common-sense measure to provide Urban Indian Health Programs with the same federal protections given to all other Indian Health Care Providers.”“Minnesota’s urban Indigenous community has been hit hard by the coronavirus pandemic, yet many urban Indian health organizations are often forced to spend hundreds of thousands of dollars on costly liability protection instead of being able to use those resources to provide health care to Native community members,” said Smith. “This is unacceptable. We need to make sure that urban Indian organizations can use every dollar they have to give urban Indigenous individuals the care they need. I’m glad to work in a bipartisan way to bring financial relief to these vital organizations.” “There are two prominent UIOs in Oklahoma that faithfully serve our Tribal communities’ healthcare needs in addition to the other important Tribal health facilities around the state. I am glad our bill addresses this disparity in the law to help ensure equal access to medical malpractice liability coverage for the services they offer,” said Lankford. “Federal tort law currently omits coverage for UIOs, and especially during the coronavirus pandemic, UIOs, like other already covered Tribal health facilities, need to have the peace of mind that they can utilize their funds for care, not court cases.”“Arizona is home to four Urban Indian Organizations, all of which are forced to spend hundreds of thousands of dollars annually on liability insurance that could otherwise be spent on patients,” said McSally. “Our legislation will fix this inequity by extending federal liability coverage to our urban Indian health groups, dramatically decreasing the cost of malpractice insurance while freeing up more money for patient care. Bringing parity to Urban Indian Health is an important step to improving Native American health care across the board.” The full text of this legislation is available here.last_img read more

Sir, I read with great interest

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Simon Dicken to head new investment team for JLL

first_imgTo access this article REGISTER NOWWould you like print copies, app and digital replica access too? SUBSCRIBE for as little as £5 per week. Would you like to read more?Register for free to finish this article.Sign up now for the following benefits:Four FREE articles of your choice per monthBreaking news, comment and analysis from industry experts as it happensChoose from our portfolio of email newsletterslast_img