AD Quality Auto 360p 720p 1080p Top articles1/5READ MOREThe joys and headaches of holiday travel: John PhillipsIn response to government cuts, he has started the Students Standing Up Against the Government Club at Canyons.Robert Rodriguez, a candidate for Congress, attended the small public gathering. Rodriguez, a Democrat, is challenging U.S. Rep. Howard “Buck” McKeon, R-Santa Clarita, for his long-held seat. “I have $13,000 out in student loans myself,” said Rodriguez, who attended UCLA and Harvard. “There is no way I could have paid for my education if it weren’t for student loans.”Diana Shaw, a Santa Clarita resident, has a son enrolled at Arizona State University. Shaw is angry about these cuts and hikes because she has been ill for a year, and her son has had to find ways to fund his own education.“He is already working 40 hours a week to pay for college,” Shaw said. “I am outraged that while the government can spend billions in Iraq killing my son’s friends they can’t come up with a reasonable interest rate for my son.” This increase means that the average student, with a 30-year loan, will pay an additional $13,000 over the life of the email@example.com(661) 257-5254160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! VALENCIA – A small group of students and parents gathered Friday at College of the Canyons to protest a bill approved by Congress that increases the costs of student loans.Congress recently approved a $12.7 billion cut to government funds for subsidized loans and increased student loan interest rates by almost 2.5 percent.“The government has all these loan programs in place to invest in us and this country and then makes them inaccessible,” said Kyle Kostvzewa, a political science major. “It doesn’t make sense.”Kostvzewa has no student loans yet, but plans to borrow when he moves on the University of California at Los Angeles.
Sudafrika hat die Transportinfrastruktur einer Industrienation. Die Strassen sind erstklassig. Das Flug- und Schienennetz ist das Großte auf dem Kontinent. Und die Hafen des Landes bieten einen naturlichen Zwischenlandungspunkt fur die Schifffahrt von und nach Europa, den Amerikas, Asien, Australasien und beide Kusten Afrikas.Die Transportbranche wurde von der Regierung als einer der Hauptfaktoren zur Verbesserung der sudafrikanischen Wettbewerbsfahigkeit im weltweiten Markt anerkannt. Sie wird in zunehmendem Maße als Motor fur wirtschaftliches Wachstum und soziale Entwicklung gesehen.2010 Fifa Fußball-WMSudafrika plant Ausgaben in Hohe von 9 Milliarden Rand zur Verbesserung und Erweiterung der Transportinfrastruktur in den neun Spielstadten, um den massiven Besucherzustrom bei der Fifa Fußball-WM 2010 bewaltigen zu konnen.In Vorbereitung sind Großmodernisierungen der Flughafen des Landes sowie Verbesserungen im Beforderungswesen, u. a. ein Taximodernisierungsprogramm, die Vereinheitlichung des Zugverkehrs und eine Umstrukturierung des Busverkehrs.Hafen und SchifffahrtHauptschifffahrtsrouten fuhren an Sudafrikas Kuste entlang in den Sudatlantik und den Indischen Ozean. Auf dem Seeweg finden ca. 96% der Exporte Sudafrikas statt und die sieben Handelshafen sind die Handelsadern zwischen Sudafrika und den anderen Partnern im sudlichen Afrika sowie Dreh- und Angelpunkte fur den Handel mit Europa, Asien, Nord- und Sudamerika und der Ost- und Westkuste Afrikas.Die staatliche Behorde Transnet National Ports Authority verwaltet die Hafen des Landes. Diese Hafen sind: Richards Bay und Durban in KwaZulu-Natal, East London und Port Elizabeth am Ostkap und Mossel Bay, Kapstadt und Saldanha am Westkap.Durban ist Afrikas geschaftigster Hafen und hat die großte Containeranlage Afrikas, wahrend Richards Bay der weltgroßte Bulkterminal fur Kohle ist. Zusammen genommen haben Sudafrikas Hafen 2007 183 Mio. Tonnen Fracht umgeschlagen. Umfangreiche Erweiterungen sind in der Vorbereitung, um die Kapazitaten zu steigern.Ein achter Handelshafen (Ngqura) ist derzeit in Entwicklung vor der Kuste von Port Elizabeth in der Provinz Ostkap. Die Inbetriebnahme ist fur 2009 vorgesehen. Nqura wird der tiefste Containerterminal in Afrika sein. Das Areal gehort als wesentlicher Bestandteil zu Coega, einer der strategischen Industrieentwicklungszonen in Sudafrika.StraßenSudafrikas Straßennetz umfasst ca. 754.000 Kilometer, von denen 9.600 km auf befestigte Nationalstraßen entfallen. Die Fahrt von Messina an der sudafrikanischen Nordgrenze bis nach Kapstadt im Suden ist eine Reise uber 2.000 km auf gut unterhaltenen Straßen.Ca. 2 400 km des Straßennetzes sind mautpflichtig.Wahrend das Verkehrsministerium die Leitlinien vorgibt, obliegt der Bau von Straßen und deren Instandhaltung er South African National Roads Agency sowie den neun Provinzen und den Kommunen.EisenbahnSudafrikas hat ein großflachiges Schienennetz – das zehntgroßte der Welt – das an die Schienennetze Schwarzafrikas angebunden ist.Die staatliche Gesellschaft Transnet Freight Rail ist die großte Bahngesellschaft und Schwerlastspedition im sudlichen Afrika mit einem Schienennetz von 22.000 km, von denen 1.500 km fur den Schwerlastverkehr geeignet sind. Die Schieneninfrastruktur des Unternehmens verbindet die Hafen mit den restlichen Landesteilen und macht ca. 80% des gesamten afrikanischen Bahnnetzes aus.Die Regierung hat ein Projekt zur Verbesserung der Bahnsicherheit und zur Neubelebung des Zuges als offentliches Verkehrsmittel gestartet. 2008 hat die Regierung Investitionen in Hohe von 19,5 Milliarden Rand pro Jahr uber einen Zeitraum von vier Jahren zur Modernisierung der Hafen und der Bahninfrastruktur angekundigt. Davon ist die Halfte fur den Schienenfrachtverkehr vorgesehen.Die South African Rail Commuter Corporation betreibt die Metrorail-Nahverkehrszuge in Kapstadt, in der Provinz Ostkap sowie in Durban und im Großraum Johannesburg/Pretoria. Diese Zuge werden hauptsachlich von weniger reichen Sudafrikanern benutzt.Fur Touristen und andere gut betuchte Passagiere bietet sich der Blue Train, einer der beruhmtesten Luxuszuge weltweit. Shosholoza Meyl befordert wahrend dessen ca. vier Millionen Fahrgaste zwischen den wichtigsten Stadten des Landes.Zugverbindungen bestehen ebenfalls mit anderen Landern im sudlichen Afrika (Simbabwe, Mosambik und Swaziland).Gautrain Rapid Rail LinkDer Gautrain, ein 80 km langes Schnellzugnetz, wird Johannesburg und Pretoria mit dem OR Tambo International Airport verbinden und bietet gleichzeitig eine sichere und bequeme Alternative zu den haufigen Staus auf der Autobahn von Johannesburg nach Pretoria.Das 25-Milliarden-Rand-Projekt ist eine Partnerschaft zwischen der Provinz Gauteng und der privatrechtlichen Bombelo Concession Company, einem kanadisch-franzosisch-sudafrikanischen Konsortium. Es wird geschatzt, dass der Gautrain bis 2009 etwa 33.000 Arbeitsplatze schafft.24 Zuge werden 18 Stunden am Tag mit einer Reisegeschwindigkeit von 160 km/h verkehren, mit einem veranschlagten Fahrgastaufkommen von 135.000 pro Tag. Fur den Zubringertransport von und zum Bahnhof und zu nahe gelegenen Zielen werden Luxusbusse bereitstehen.Es wird 10 Haltepunkte geben, 3 davon unterirdisch. Der unterirdisch gefuhrte Streckenabschnitt wird 14 km lang sein und an manchen Stellen bis zu 96 m unter der Oberflache verlaufen.Die erste Phase, der Abschnitt zwischen dem Flughafen, Sandton und Midrand, wird rechtzeitig zur Fifa Fußball-WM 2010 fertig gestellt. Die Fertigstellung der zweiten Phase ist fur 2011 vorgesehen.Flughafen und FluggesellschaftenÜber 50 Fluggesellschaften mit 230.000 Landungen und uber 33 Mio. Passagieren pro Jahr verkehren an den zehn sudafrikanischen Hauptflughafen. Dazu gehoren auch die drei wichtigsten internationalen Flughafen Johannesburg, Kapstadt und Durban, sowie die Flughafen Port Elizabeth, East London, George, Kimberly, Upington, Bloemfontein und Pilansberg.21 Fluguberwachungszentren uberwachen den Betrieb von 145 lizenzierten Kleinflughafen mit asphaltierten Landebahnen und mehr als 580 Flugplatzen mit unasphaltierten Landebahnen.Die halbprivatisierte Gesellschaft Airports Company South Africa (Acsa) ist fur die Koordination der Infrastrukturerweiterung auf den Flughafen des Landes zustandig.2007 legte Acsa den Entwurf fur ein funfjahriges Kapitalaufstockungsprogramm im Werte von fast 20 Milliarden Rand vor, um die Flughafen auf die neue Flugzeuggeneration vorzubereiten und um das Passagieraufkommen bewaltigen zu konnen.Der Johannesburger OR Tambo International Airport ist Afrikas meistfrequentierter Flughafen mit ca. 8,9 Mio. Passagieren pro Jahr. Er wurde 2007 vom Airports Council International zum besten Flughafen des Kontinents gekurt.Cape Town International mit 3,8 Millionen Passagieren pro Jahr wurde zum fuhrenden Flughafen Afrikas gewahlt und erhielt uber sieben Jahre in Folge die Auszeichnung World Travel Award.South African Airways, Sudafrikas nationale Fluggesellschaft, fliegt uber 700 Stadte an (darunter 20 Ziele in Afrika) und bietet Wartungsdienstleistungen fur eine Vielzahl von anderen Fluggesellschaften in der Welt.Letzte Aktualisierung: September 2008SAinfo reporter. Quellen (Englische Websites):Standard Bank: Economic Profile: South AfricaSouth Africa YearbookDepartment of TransportTransnet National Ports AuthorityCoega Development CorporationTransnet Freight RailSouth African Rail Commuter CorporationGautrain Rapid Rail LinkAirports Company South AfricaSouth African Airways
Travellers arriving at Zurich airportduring the World Economic Forum earlierin 2010 were greeted by stunning SouthAfrican vistas.(Image: IMC) MEDIA CONTACTS • Chantal WellingtonIMC digital content manager+27 11 483 0122MediaClubSouthAfrica.com reporterAnitha Soni, chairperson of the board of trustees of the International Marketing Council of South Africa (IMC), will receive the Brand Leadership Award at the 19th World Brand Congress in Mumbai, India, later in November.Described as the most prestigious award an individual can receive at the congress, the award is one of several accolades to be given. Others include CEO of the Year, Media Professional of the Year, and Brand Builder of the Year.The World Brand Congress represents 60 countries. Some 600 branding and marketing specialists are expected to participate in the 2010 event.Soni, a tourism specialist and award-winning businesswoman, will be honoured for her “professional efforts” in overseeing the activities of the IMC, as it delivers on its mandate to manage the country’s reputation, and position South Africa as an investment destination of choice.Under her guidance, the IMC is delivering on this mandate, both domestically and internationally. The most recent and highest-profile example is the 2010 Fifa World Cup – here the IMC’s mobilisation initiatives engendered strong social cohesion among South Africans, fulfilling the country’s 2010 brand promise to “celebrate Africa’s humanity”.She was also instrumental in the council’s drive to position South Africa’s business and economic competitiveness at the 2010 meeting of the World Economic Forum in Davos, which saw a powerful delegation of political and business leaders departing for Switzerland to promote the country’s agenda.While at the congress Soni will deliver a speech titled “The impact of international events on a nation’s pride and therefore its brand – sharing South Africa’s 2010 World Cup experience”.Passionate about South AfricaSoni believes the award does not belong to her alone, but to all the role players in government and the private sector that participate in building the country’s brand.“The IMC is the custodian of Brand South Africa, but the brand belongs to all South Africans,” she said. “The World Cup has shown that when South Africans act with unity of purpose, everyone contributes to growing our reputation on the international stage.“The primary role players responsible for enhancing the nation brand are dedicated, skilled and passionate about our country. This past year they have worked with great diligence to foster relationships, engage with international stakeholders and promote South Africa.”Soni added that the award belongs to everyone who contributed to South Africa’s enhanced global reputation, and that she would think of all South Africa’s brand builders when the award was placed in her hands.
1 July 2011 The Industrial Developmental Corporation (IDC) approved funding of R8.4-billion for the year ending March 2011. The funding, its highest ever for South African-based investments, is expected to create up to 20 000 full-time jobs and save an additional 11 000 jobs. “This is the highest level ever for South African-based investments,” the IDC said in its annual financial results, published on Thursday. “Funding approvals during the year under review are expected to create 19 650 full time jobs and save an additional 11 650, with a combined impact on employment of 31 300, up from 25 000 in 2010. “An additional 8 100 jobs are expected to be created through direct linkages to activities in the informal economy.” The IDC posted a R2.7-billion profit due to improved profitability from operations, performance of equity accounted investments, containment of operating expenses and lower impairments. The IDC said the South African economy had recovered steadily from the recent recession, with the pace of growth gaining momentum towards the latter part of 2010 and firming in the opening quarter of 2011.High-impact manufacturing “We have retained our focus both on preserving and growing high-impact manufacturing capacity, and have succeeded in improving our impact on job creation,” IDC CEO Geoffrey Qhena said. Of the total amount of funding approvals, 97 percent were in the priority sectors identified in the government’s New Growth Path (NGP), including manufacturing, infrastructure, agriculture and the mining value chain. Forty-nine percent of funding approvals went to developments in provinces other than Gauteng, Western Cape and KwaZulu-Natal in order to ensure provincial equity. “The IDC continues to leverage its portfolio to improve development outcomes. This includes creating ring-fenced schemes to subsidise industry development, such as the R10-billion Gro-e-Scheme with concessionary terms aimed at job creation, which was launched in February 2011,” said Qhena. Over 17 000 jobs were created and saved as a result of the R2-billion UIF scheme launched in May last year, R1.5-billion of which has already been approved. The corporation has also approved R4.1-billion of the R6-billion allocated to assist companies in distress. “IDC will make available R102-billion over the next five years for investment. To achieve this level of investment, the partnership of various stakeholders and social partners is key. These include businesses, co-funders, labour, government and civil society,” said Qhena. In his budget vote in April, Economic Development Minister Ebrahim Patel said that, over the next five years, “green” industries would be allocated R22.4-billion, while mining and beneficiation would be allocated R22.1-billion. Manufacturing would receive R20.8-billion, while the agriculture value chain would receive R7.7-billion. Source: BuaNews
NEW DELHI—Inspired by this past April’s global march for science, Indian scientists are gearing up for their own march in more than 30 cities on 9 August, organizers announced today. Their main beefs are anemic science funding and growing religious intolerance.India’s science investments are minuscule compared with those of China and South Korea, says Prabir Purkayastha of the nonprofit Delhi Science Forum. One pillar of Indian R&D that’s suffering, he says, is the Indian Institutes of Technology (IIT), a nationwide network of 23 research and teaching institutions. “IITs today have second rate infrastructure compared to what they need and barring a few, there are no institutes in India which have the kind of money required for the next generation of science,” Purkayastha says. He and other march organizers are demanding that the Indian government boost R&D spending as a percentage of gross domestic product from roughly 0.85% in 2016 to 3% of GDP. By Sanjay KumarAug. 4, 2017 , 3:55 PM Indian scientists taking to streets en masse Breakthrough Science Society Government officials say that the march organizers’ complaints are overblown. “Their position is factually incorrect,” says Ashutosh Sharma, secretary of the central government’s Department of Science & Technology here. Science spending is booming, he says. “In the past 3 years, our budget has nearly doubled compared to earlier periods for both basic and applied research,” he says. Purkayastha counters that government departments are diverting funds marked for R&D to nonresearch programs.Organizers are also calling on Indian officials to steer clear of pseudoscience and instead promote a scientific temper: a spirit of inquiry enshrined in India’s constitution. “Unscientific and superstitious beliefs are being propagated around in a big way, and we see government’s hand in promotion of these ideas which has made scientists extremely unhappy,” says Soumitra Banerjee, an engineering professor at the Indian Institute of Science Education & Research in Kolkata. Banerjee, who is also general secretary of Breakthrough Science Society in Kolkata, a nonprofit that is spearheading the march, hopes next week’s marches are not a one-off event. “This movement is likely to gain more momentum,” he says.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*) Scientists on the march in Bengaluru, India, in 2014. Marches in more than 30 cities are planned for next Wednesday.
Ajinkya Rahane admits he was stunned to be named India captain for their upcoming Zimbabwe series, after being dropped just a week earlier, and while he plans to draw inspiration from past skippers he also wants to make his own mark on the team.Rahane, who averages a tad over 30 in one-day internationals, played the first of India’s three-match series against Bangladesh at Mirpur and scored nine off 25 balls as they went down by 79 runs.He was dropped for the next two matches, with regular captain Mahendra Singh Dhoni saying the 27-year-old’s batting was more suited to pitches offering more pace.But that did not stop India from putting Rahane in charge of a second-string squad for this month’s tour of Zimbabwe for three ODIs and two Twenty20 internationals while resting Dhoni and a host of other senior cricketers.”The decision of naming me captain did come as a surprise because I wasn’t thinking about captaincy ever,” Rahane, who has played 55 ODIs, told the Indian cricket board’s website (BCCI.TV). “I didn’t know how to react when I heard the news.”Once the news slowly began to sink in, I became really confident of handling this new responsibility.”The 2-1 ODI series loss was India’s first to Bangladesh, and another loss against Zimbabwe would not go down well with the country’s cricket-crazy fans despite the lack of senior players in the touring party.Rahane, a regular in India’s test side, has had the opportunity to play under Dhoni, new test captain Virat Kohli and also former skipper Rahul Dravid while playing for the Rajasthan franchise in the Indian Premier League.advertisementHe said he would tried to emulate different qualities from all of them.”Firstly, playing under MS Dhoni I would observe how he would be calm on the field. He has a very peculiar and calm way of handling situations,” the Mumbai batsman added. “I would like to take that quality from him.”What I would like to take from Virat Kohli would be controlled aggression. You can see that quality in his batting and his captaincy.”And finally, Rahul bhai is someone who likes to keep things really simple on the field, which I got to know while playing under him with the Rajasthan Royals.”Having said that, I have my own set of ideas and I know what I have to do on the field.”
February 1, 2017Welcome to the January 29. 2017 workshop participants.from left:Emily Mather,Joseph Islas,Kendra Dahm [scholarship],Harmann Panchal from Strathclyde University in Scotland,Hnin Su Mon Win from Strathclyde University in Scotland,Thomas Geusz [scholarship],Jerry Puerner,Dev Aujla [seminar week and week 2].[photo by Sue Kirsch]
Source:https://sahlgrenska.gu.se/english/research/news-events/news-article/?languageId=100001&contentId=1603898&disableRedirect=true&returnUrl=http%3A%2F%2Fsahlgrenska.gu.se%2Fforskning%2Faktuellt%2Fnyhet%2F%2Fny-kunskap-kring-nybildning-av-nervceller-i-hjarnan.cid1603898 Reviewed by James Ives, M.Psych. (Editor)Jan 3 2019Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada, and Slovenia, have discovered a novel and unexpected function of nestin, the best known marker of neural stem cells.In the developing brain, the 3 main cell types, specifically neurons, astrocytes and oligodendrocytes, are generated from neural stem cells. In some parts of the brain, such as the hippocampus, the brain region involved in learning and memory, new neurons are being added to the existing neuronal circuitry even in the adulthood when severe restriction of neuronal differentiation occurs.Related StoriesMercy Medical Center adds O-arm imaging system to improve spinal surgery resultsRush University Medical Center offers new FDA-approved treatment for brain aneurysmsNew therapy shows promise in preventing brain damage after traumatic brain injuryUsing mice deficient in nestin, a protein that is a component of the part of the cytoskeleton known as intermediate filaments or nanofilaments, the research team led by Prof. Milos Pekny showed that nestin produced in astrocytes has an important role in inhibiting neuronal differentiation. They linked this regulatory function of nestin to the Notch signaling from astrocytes to neighboring neural stem cells. Thus, surprisingly, nestin does not control the generation of neurons by acting within neural stem cells, but indirectly by regulating the neurogenesis-inhibitory Notch signals that neural stem cells receive from astrocytes, important constituents of the neurogenic niche.Generation and functional integration of new neurons in the adult mammalian hippocampus can lead to the reorganization of the neuronal circuitry, triggering 2 opposing effects: a better formation of new memories and a more pronounced loss of previously acquired memories. And indeed, adult mice lacking nestin have both increased number of newly born neurons in the hippocampus and impaired long-term memory.Intermediate filament proteins, or nanofilament proteins as they are sometimes called, are important stress proteins that in many cell types act as crisis command centers in times of cellular stress and emerge as interesting targets in many diseases – says Milos Pekny. They are also linked to the control of cell differentiation and in the brain or spinal cord their regulation might be a new approach for improving brain plasticity and regeneration responses in situations such as stroke, neurotrauma or neurodegenerative diseases.Our study adds to the list of important functions of astrocytes in the central nervous system, the cells that we increasingly view as the brain of the brain, a system that controls many processes in healthy and diseased brain – explains Ulrika Wilhelmsson.
Source:https://www.elsevier.com/ Reviewed by Kate Anderton, B.Sc. (Editor)Feb 4 2019Sinks situated next to patient toilets in hospital rooms may be reservoirs for Klebsiella pneumoniae carbapenemase (KPC), increasing the risk of dangerous germ transmission, according to new research published in the American Journal of Infection Control (AJIC), the journal of the Association for Professionals in Infection Control and Epidemiology.The study found a high prevalence of KPC positivity in sink drains located next to toilets. Of the samples tested, 87.0 percent of patient sinks next to toilets tested positive for KPC – in stark comparison to the 21.7 percent of sink drains located closer to the entry door of the room.Related StoriesA bacterium may limit cardiovascular risks of 1 in 2 people, study showsNew research could help design algae that produces fuels and cleanup chemicalsNon-pathogenic bacteria engineered as Trojan Horse to treat tumors from withinKlebsiella is a type of bacteria that can cause a number of healthcare associated infections, such as pneumonia, bloodstream infections, wound infections, or surgical site infections. Increasingly, Klebsiella bacteria have developed antimicrobial resistance, most recently to the class of antibiotics known as carbapenems.In four of five rooms in which the entry-door sink tested positive, the sink near the toilet was also positive, suggesting a potential source for cross-contamination within the same room.Researchers in Milwaukee, Wisconsin performed the study in the medical intensive care unit (MICU) of a 600-bed Wisconsin hospital. The MICU did not have any documented interactions with KPC-producing organisms within the past year.”This study, if validated, could have major implications for infection control,” agree study authors, Blake Buchan, PhD, and Silvia Munoz-Price, MD, PhD. “If sinks next to toilets are indeed a reservoir for KPC, additional interventions – such as modified hand hygiene practices and sink disinfection protocols – may be needed to stem the risk of transmission among healthcare providers and patients alike.”This is the first study to directly examine the relevance of sink proximity to toilets in patient rooms. The researchers point out that while it is not clear how contamination occurs, it is plausible that biofilms growing in pipes shared between toilets and sinks or that flushing generates contaminated drops that reach the sink drains.”The results of this study demonstrate the importance of remaining vigilant to potential areas of cross-contamination,” said 2019 APIC President Karen Hoffmann, RN, MS, CIC, FSHEA, FAPIC. “Maintaining a strong understanding of environmental risks is critical to protecting patient safety, and this is yet another example of how germs can lurk in often the most unexpected of places.”
An EU court said the Commission’s emissions limits were ‘too high’ Safeguarding compliance with new vehicle emissions legislation The General Court “annuls in part the (European) Commission’s regulation setting excessively high oxides of nitrogen emission limits for the tests for new light passenger and commercial vehicles,” it said.The Commission, the EU’s executive arm, aimed to set new norms to what existed already for emissions tests conducted in the laboratory but which lawmakers said accounted for differences in real driving conditions.By chance, the new limits were set weeks after the “Dieselgate” scandal erupted three years ago.Emissions laws have been a key target for environmental activists since the scandal erupted in 2015, when Volkswagen admitted to manipulating 11 million diesel vehicles worldwide to cheat regulatory emissions tests.But the General Court, based in Luxembourg, upheld the actions taken by the cities of Paris, Brussels and Madrid to annul the limits set by the Commission.”They submit that the Commission was not entitled to adopt the oxides of nitrogen emission values selected because they are less demanding than the limits set by the applicable Euro 6 standard,” the court said.The Euro 6 standard was set in 2007 by the European Parliament and the EU member countries concerning emissions from light passenger and commercial vehicles.The court ruled “the Commission did not have the power to amend the Euro 6 emission limits for the new real driving emission tests.” The court went further.”Even if it had to be accepted that technical constraints may justify a certain adjustment, a difference such as that stemming from the contested regulation means that it is impossible to know whether the Euro 6 standard is complied with during those tests.” This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: EU court rejects ‘excessively high’ diesel emissions limits (2018, December 13) retrieved 17 July 2019 from https://phys.org/news/2018-12-eu-court-excessively-high-diesel.html An EU court on Thursday rejected the “excessively high” diesel emissions limits Brussels set just after the scandal in which German carmaker Volkswagen cheated on emissions tests. Explore further © 2018 AFP